WebJul 3, 2024 · Of the corresponding gene products, PLIN2 is the only constitutive and … WebSep 9, 2024 · A recent study showed that the generation of ROS can increase perilipin 2 (Plin2) expression in HepG2 cells. Some evidence has also demonstrated the association between Plin2 expression and renal tumors. However, the underlying mechanism of Plin2 in I/R-induced acute kidney injury (AKI) remains elusive. Here, using a mouse model of I/R …
Parallel CRISPR-Cas9 screens reveal mechanisms of PLIN2 and …
WebNov 18, 2014 · Although perilipin 2 (Plin2) has been shown to bind lipids with high affinity, the Plin2 lipid binding site has yet to be defined. This is of interest since Plin2's affinity for lipids has been suggested to be important for lipid droplet biogenesis and intracellular triacylglycerol accumulation. To define these regions, mouse Plin2 and several ... WebAug 28, 2024 · Lipid droplets (LDs) are lipid storage organelles that consist of a central core of neutral lipids surrounded by a phospholipid monolayer decorated with a unique set of integral and peripheral proteins. Invariably, at least one member of the perilipin family of proteins (PLIN1-5) associates with LDs in all cell types. Despite key roles of PLIN2 in … fly bum song
Accurate liquid biopsy for the diagnosis of non-alcoholic ... - Gut
WebSep 26, 2024 · The role of perilipin 2 in Pseudomonas aeruginosa pulmonary infection. Rab18 binds PLIN2 and ACSL3 to mediate lipid droplet dynamics. Lipid droplets are both highly oxidized and Plin2-covered in hepatocytes of diet-induced obese mice. Perilipin2 inhibits diabetic nephropathy-induced podocyte apoptosis by activating the PPARgamma … WebFeb 8, 2024 · RDH/CG2064 interacts with the lipid droplet-resident protein Plin2 and the RDH/CG2064-Plin2 axis acts to reduce the overall level and lipid droplet localization of Bmm/ATGL lipase. This axis is important for larval survival under prolonged starvation. Thus, we discovered an RDH-Plin2 axis modulates lipid droplet size. WebMonoclonal Antibody for studying perilipin. Cited in 227 publications. Validated for WB, IP, IHC, IF, IF. Available in 2 sizes. Highly specific and … fly bundaberg to brisbane