Ctbp ogdhl

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August undefined, 2024

WebAug 5, 2024 · OGDHL oxoglutarate dehydrogenase L Gene ID: 55753, updated on 5-Aug-2024 Gene type: protein coding Also known as: YOBELN See all available tests in GTR for this gene Go to complete Gene record for OGDHL Go to Variation Viewer for OGDHL variants Summary WebOGDHL has 3,312 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 66 datasets. Click the + buttons to view associations for ...

OGDHL is a modifier of AKT-dependent signaling and NF …

WebThe CTP Portal is intended for use by regulated tobacco Industry, including manufacturers, importers, and distributors who make submissions to CTP. The CTP Portal should … WebOgdhl: Name: oxoglutarate dehydrogenase L: RGD ID: 1310916: Description: Predicted to enable oxoglutarate dehydrogenase (succinyl-transferring) activity. Involved in 2-oxoglutarate metabolic process and tricarboxylic acid cycle. Predicted to be located in mitochondrial matrix. Predicted to be part of oxoglutarate dehydrogenase complex. critical regionalism charles correa

The Potential of Metabolism-Related Gene OGDHL as a …

WebMay 1, 2024 · To further examine the functional impacts of OGDHL in hepatoma cell progression, we constructed shRNA-OGDHL-knockdown clones (sh-A and sh-B) in Bel … WebThe overexpression of OGDHL also markedly suppressed the growth of HCC-LM3/OGDHL xenograft tumors in immunodeficient mice (p = 0.014; Figure 8C,D); these findings were … critical regionalism in kerala

Tissue expression of OGDHL - Summary - The Human Protein Atlas

Silencing of OGDHL promotes liver cancer metastasis by …

WebAug 5, 2024 · OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism. OGDHL closely associates with tumor microenvironment and can … WebOGDHL Is a Modifier of AKT-Dependent Signaling and NF-kB Function Tanusree Sen1, Nilkantha Sen2, Maartje G. Noordhuis1, Rajani Ravi1, T-C Wu3, Patrick K. Ha1,4, David Sidransky1, Mohammad Obaidul Hoque1* 1Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United … critical regionalism pdfWebMar 21, 2024 · OGDHL (Oxoglutarate Dehydrogenase L) is a Protein Coding gene. Diseases associated with OGDHL include Yoon-Bellen Neurodevelopmental Syndrome … critical regionalism revianto budi santoso

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Ctbp ogdhl

Web17110-1-AP targets OGDHL in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH … WebApr 9, 2024 · CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor; NM_001377187.1 → NP_001364116.1 C-terminal-binding protein 1 isoform 4. Status: REVIEWED. Source sequence(s) AC092535 Consensus CDS CCDS93461.1 UniProtKB/TrEMBL H0Y8U5 Conserved Domains (1) summary …

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WebThe pro-metastatic role of OGDHL downregulation is most likely attributed to its upregulation of HIF-1α transactivation activity and the protein stabilization by promoting the accumulation of L-2-HG to prevent the activity of HIF-1α prolyl hydroxylases, which subsequently causes an epithelial–mesenchymal transition process in HCC cells. WebOGDHL (FLJ10851) protein expression summary. The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glu cose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria.

WebJul 22, 2024 · Hepatocyte-specific SIRT5 overexpressing mice (liver SIRT5 OE) were generated to address the possible involvement of hepatic SIRT5 in AMI. The areas of myocardial infarction, myocardial fibrosis, and cardiac function in a model of experimental myocardial infarction were compared between liver SIRT5 OE mice and wild-type (WT) … WebJan 12, 2024 · OGDHL is predicted to be a thiamine diphosphate-dependent 2-oxo acid dehydrogenase ( EC 1.2.4.2) for reduction of protein-bound lipoyl groups ( Bunik and Degtyarev, 2008 ). OGDHL encodes a rate-limiting enzyme in the Krebs cycle that plays a pivotal role in mitochondrial metabolism ( Yap et al., 2024 ). Cloning and Expression

WebJan 25, 2024 · The ketoglutarate dehydrogenase complex (KGDHC) consists of three different subunits encoded by OGDH (or OGDHL), DLST, and DLD, combined in different stoichiometries. DLD subunit is shared between KGDHC and pyruvate dehydrogenase complex, branched-chain alpha-keto acid dehydrogenase complex, and the glycine … WebAug 5, 2024 · Gene ID: 55753, updated on 5-Aug-2024 Summary The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria.

WebImmunohistochemistry of paraffin-embedded human brain using 17110-1-AP (OGDHL antibody) at dilution of 1:100 (under 10x lens). Mouse kidney tissue were subjected to …

WebJan 14, 2024 · In a 15-year-old girl (BAB4852), born of consanguineous Turkish parents, with Yoon-Bellen neurodevelopmental syndrome (YOBELN; 619701), Yoon et al. (2024) identified a homozygous c.2333C-T transition (c.2333C-T, NM_018245) in exon 18 of the OGDHL gene, resulting in a ser778-to-leu (S778L) substitution at a conserved region in … critical regionalism architectureWebDec 2, 2024 · We identified nine individuals from eight families carrying bi-allelic variants in the OGDHL gene through whole-exome sequencing (WES) (Figure 1 A). All groups were … mankato convention center hotelWebThe CtBP1 protein was originally identified as a human protein that bound a PLDLS motif in the C-terminus of adenovirus E1A proteins. It and the related protein CTBP2 were later shown to function as transcriptional corepressors. [7] That is, regulatory proteins that bind to sequence-specific DNA-binding proteins and help turn genes off. critical recap campaign 3 episode 51WebJan 12, 2024 · OGDHL is predicted to be a thiamine diphosphate-dependent 2-oxo acid dehydrogenase (EC 1.2.4.2) for reduction of protein-bound lipoyl groups (Bunik and … mankato delivery serviceWebOGDHL 抗体可用于分析细胞对 OGDHL si/shRNA基因沉默的应答点击图片或放大按钮来放大 RNAi-directed mRNA Cleavage 基因信息 siRNA Primer shRNA Plasmid shRNA 慢病毒颗粒介绍 10 µM，50-100次转染 siRNA产品通常包含3-5种目标特异的19-25 nt的siRNA，用于敲除基因表达如果需要确认某一种siRNA单独沉默OGDHL基因效果，可以申请单独购买 … mankato dental artsWebConclusion: Our findings established that silencing of OGDHL contributed to HCC development and survival by regulating glutamine metabolic pathways. OGDHL is a … mankato custom carsWebOct 17, 2024 · Background and Objective . Liver cancer is a highly malignant tumor, and patients typically have poor prognoses. Metabolic reprogramming is a hallmark of cancer, and downregulation of … mankato dental hygiene program